Marla wrote on Aug 3^rd, 2025 at 3:02pm:

...your brain rotting?
Wow. How spiritual of you man.

Peccary has a ghost in his home.
Do you think Marla is experiencing the paranormal?

Marla wrote on Aug 20^th, 2025 at 5:34am:


Man - you should just go cold turkey ... it IS a far better world out there without that sht, man.... your natural abilities to perceive the world are far better than some drug-induced halogen of delusion ... man.... being yourself is a far greater high than you can get from that sht ...

Love it, wah-kahn-yeh-jah... the sky and the plains are something you can feel in your soul and see as life.... your seeking life in death of your spirit and mind is not a good thing... this I say to you three times... go to the real life spirit lodge... the other way is the path of falling into nothing... seek the ways of the spirit... purge yourself of these things ... meditate on the shores of a clear stream from the snows...drink only the good pure water... find yourself for all humanity of the People, and make of yourself your true spirit.

Hey-a-mata keya hata!

Weeds one of the favourite drugs of the cope-o-sphere.

Just trying to cope

Just trying to numb the pain of my boring existence.

It's a marker for failures

The excellent Dr Andrew Huberman has several episodes on how it punches Swiss cheese holes in the brain.

Like a self administered lobotomy for people who can't embrace the challenges of life

aquascoot wrote on Aug 21^st, 2025 at 5:29am:




The Effects of Cannabis (Marijuana) on the Brain & Body | Huberman Lab Podcast #92






Oct 3, 2022  Huberman Lab

In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one’s propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents.



Timestamps

00:00:00 Cannabis (Marijuana)
00:04:46 New Huberman Lab Premium Membership
00:07:03 Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety
00:10:08 Levels, Thesis, InsideTracker
00:14:01 Momentous Supplements
00:15:08 Cannabis Strains, Psychoactive Compounds: THC & CBD
00:19:34 Sativa vs. Indica, Stimulant vs. Relaxation Effects
00:25:55 Hybrid Cannabis Strains, Type 1, 2 & 3 Strains
00:30:41 AG1 (Athletic Greens)
00:31:56 Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1)
00:40:35 THC, CBD vs. Endogenous Cannabinoids, Dependence
00:43:14 Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function
00:53:07 Biological Effects of Cannabis
00:56:29 Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia
01:04:58 Cannabis Indica & Subjective Effects, Memory, Dosage
01:09:41 Brain Areas Affected by THC & CBD, Side Effects
01:16:08 Creativity: Convergent vs. Divergent Thinking & Dopamine
01:26:41 Does Cannabis Increase Creativity?
01:35:08 Chronic Cannabis Use & Changes in Speech Patterns
01:46:46 Cannabis & Libido, Dopamine & Prolactin
01:56:55 Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility
02:06:53 Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences
02:10:06 Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development
02:18:13 Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance
02:25:57 Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis
02:34:36 Adolescent Cannabis Use: Brain Development & Mental Health Disorders
02:41:44 Cannabis & Pain Management, Divergent Effects of Cannabis
02:44:54 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Premium Channel, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn

Perfect 👍 — here’s a clear side-by-side comparison of MRI findings for short-term (acute) vs long-term (chronic) marijuana use:


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🧠 MRI Evidence: Marijuana and the Brain

🔹 Short-term (acute use) — within hours of consumption

(mostly fMRI and blood flow studies)

Increased blood flow to the frontal cortex, temporal lobes, and cerebellum (linked to altered perception, coordination, and attention).

Altered functional connectivity in the default mode network (DMN) → explains mind-wandering, introspection, and “time distortion.”

Striatum activity changes → altered reward sensitivity, “high” feeling.

Cerebellum overactivation → impaired motor control and coordination.

Memory disruption → hippocampus shows reduced efficiency during short-term recall tasks.

Emotional regulation → heightened amygdala reactivity, making users more sensitive to stimuli.


👉 Most of these acute effects resolve once the drug wears off.


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🔹 Long-term (chronic or heavy use) — weeks, months, years

(mostly structural MRI & DTI)

Grey matter reduction in:

Hippocampus → weaker memory formation.

Orbitofrontal cortex → impaired decision-making and planning.

Amygdala → emotional regulation changes.


White matter integrity changes (shown by DTI):

Especially in the corpus callosum and fronto-limbic tracts, reducing brain region communication efficiency.


Functional changes:

Altered default mode network (DMN) connectivity even at rest.

Prefrontal cortex shows compensatory hyperactivation during tasks (working harder to achieve normal performance).


Reward system dampening → chronic users show less striatal response to natural rewards (food, social interaction), tied to amotivation in some.

Age of onset effect:

Adolescents/young adults show stronger structural changes than adults who begin later.


Reversibility:

Some functional and blood flow changes improve after 2–3 months of abstinence.

Structural changes (e.g., hippocampal volume loss) appear more persistent but may partially recover with long abstinence.




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✅ Summary in one line:

Short-term MRI findings = blood flow and connectivity changes that explain being high (distorted time, memory lapses, motor effects).

Long-term MRI findings = structural shrinkage and white matter changes in memory, motivation, and decision-making areas, especially with heavy/early use

Who to believe?
Dr huberman who has 2 pH d s and is a professor at the school of medicine at the ivy league Stamford medical school

Or

Gweg
Who has a pH d in crusty keyboards 

Greg's source, a nobody journalist on slate
Whatever that is.

I think if huberman was not being factual. His position at the prestigious Stamford medical school would be in jeopardy.

Maybe we could get dr Carl to comment.
He seems to believe he is a medical authority