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Innate immune suppression by SARS-CoV-2 mRNA vax (Read 727 times)
reggie1963
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Innate immune suppression by SARS-CoV-2 mRNA vax
Dec 4th, 2022 at 7:21pm
 
https://www.sciencedirect.com/science/article/pii/S027869152200206X

The vax destroys your immune system.

You bone heads are in for a rude shock. Carl I hope you really have taken this poo but I believe you are just a drunken troll.




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FROM CARL DUNCE THE LYING SACK OF HORSE SH*T

"The only gigantic lie we've been fed (and continue to be fed) by our governments is that Covid is mild and no more dangerous than the flu"
 
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aquascoot
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #1 - Dec 4th, 2022 at 7:47pm
 
its going to be quite hard to sort out as we have lots of different mixes.

some people had 1 or 2 or 3 or 4 vaxes and then got covid

some people had 0 vaxs and then got covid

some people have had covid and didnt know they had it

some people got covid and then had more vaxes.

how can we sort out whats what?

you might say compare those who never had a vax to those who did.

but maybe anti vaxxers are the byron bay type hippies who are vegetarian and therefore have different health profiles to other groups.



it would have been intersting at the beginning to run a trial (voluntary of course) where you were given the vax or a placebo and then followed to see how many got things like shingles and bells palsy and strokes and sudden death etc.

if those given the placebos got more things, the vax was good.
if those given the vax got more things, the vax was harmful

surely these studies were done/

even if they just did them on the original groups they developed the vaccine on.
there would have been a placebo group and a vaccine group.

surely they can publish the data from that group and let us know what the result was.

there are about 1 billion chinese who havent had the disease and who havent had an mrna vax.

this would be a great opportunity to settle this once and for all,

i'll shoot off an email to my cobber Xi

he can run the worlds largest clinical trial and steal the nobel prize back from Gates
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reggie1963
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #2 - Dec 4th, 2022 at 9:03pm
 
There is no doubt the vaccinated like AusJeff the dopey bastard, Carl the Dunce and Buzz the arse fairy are more dangerous to us than we are to them. Billions of lives will be ended by this vax and I am glad its going to happen.

The fact you pack of dumb bastards fell for the fake vidoe of the people dropping dead on the streets in China goes to show how stupid you you are. Was/Is anyone dropping dead on the streets here? NO. Yet you dumb bastards believed everything the government and TV told you.

16. Conclusions

There has been an unwavering message about the safety and efficacy of mRNA vaccinations against SARS-CoV-2 from the public health apparatus in the US and around the globe. The efficacy is increasingly in doubt, as shown in a recent letter to the Lancet Regional Health by Günter Kampf (2021b). Kampf provided data showing that the vaccinated are now as likely as the unvaccinated to spread disease. He concluded: “It appears to be grossly negligent to ignore the vaccinated population as a possible and relevant source of transmission when deciding about public health control measures.” Moreover, the inadequacy of phase I, II, and III trials to evaluate mid-term and long-term side effects from mRNA genetic vaccines may have been misleading on their suppressive impact on the innate immunity of the vaccinees.

In this paper, we call attention to three very important aspects of the safety profile of these vaccinations. First is the extensively documented subversion of innate immunity, primarily via suppression of IFN-α and its associated signaling cascade. This suppression will have a wide range of consequences, not the least of which include the reactivation of latent viral infections and the reduced ability to effectively combat future infections. Second is the dysregulation of the system for both preventing and detecting genetically driven malignant transformation within cells and the consequent potential for vaccination to promote those transformations. Third, mRNA vaccination potentially disrupts intracellular communication carried out by exosomes, and induces cells taking up spike glycoprotein mRNA to produce high levels of spike-glycoprotein-carrying exosomes, with potentially serious inflammatory consequences. Should any of these potentials be fully realized, the impact on billions of people around the world could be enormous and could contribute to both the short-term and long-term disease burden our health care system faces.

Given the current rapidly expanding awareness of the multiple roles of G4s in regulation of mRNA translation and clearance through stress granules, the increase in pG4s due to enrichment of GC content as a consequence of codon optimization has unknown but likely far-reaching consequences. Specific analytical evaluation of the safety of these constructs in vaccines is urgently needed, including mass spectrometry for identification of cryptic expression and immunoprecipitation studies to evaluate the potential for disturbance of or interference with the essential activities of RNA and DNA binding proteins.

It is essential that further studies be conducted to determine the extent of the potential pathological consequences outlined in this paper. It is not practical for these vaccinations to be considered part of a public health campaign without a detailed analysis of the human impact of the potential collateral damage. VAERS and other monitoring systems should be optimized to detect signals related to the health consequences of mRNA vaccination we have outlined. We believe the upgraded VAERS monitoring system described in the Harvard Pilgrim Health Care, Inc. study, but unfortunately not supported by the CDC, would be a valuable start in this regard (Lazarus et al., 2010).

In the end, billions of lives are potentially at risk, given the large number of individuals injected with the SARS-CoV-2 mRNA vaccines and the broad range of adverse outcomes we have described. We call on the public health institutions to demonstrate, with evidence, why the issues discussed in this paper are not relevant to public health, or to acknowledge that they are and to act accordingly. Furthermore, we encourage all individuals to make their own health care decisions with this information as a contributing factor in those decisions.
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FROM CARL DUNCE THE LYING SACK OF HORSE SH*T

"The only gigantic lie we've been fed (and continue to be fed) by our governments is that Covid is mild and no more dangerous than the flu"
 
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AusGeoff
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #3 - Dec 4th, 2022 at 10:09pm
 

Reply to “Innate immune suppression by SARS-CoV-2 mRNA vaccinations:
The role of G-quadruplexes, exosomes, and MicroRNAs”: Important concerns
on the validity of this article
.

https://osf.io/m58yh/

Quote:
We share a Letter of concern To the Editor from Food and Chemical
Toxicology about a recent published review from Seneffet al entitled
"Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role
of G-quadruplexes, exosomes, and MicroRNAs" ( doi: 10.1016/j.fct.2022.113008).
In our opinion, this article contains several assumptions and misinformation
that we highlight.

We believe that a rapid analysis of the key points and the misinterpretations
that they contain are sufficient to invalidate the relevancy of the article

and therefore we ask the editor to revise their opinion on the publication of the article.


Jérôme BARRIERE MD, Fabrice FRANK PhD, Lonni BESANCON PhD,
   Alexander SAMUEL PhD, Véronique SAADA PharmD, Eric BILLY FR,
   Barbara SEITZ-POLSKI MD,PhD, and Jacques ROBERT MD,PhD.

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AusGeoff
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #4 - Dec 4th, 2022 at 10:15pm
 
reggie1963 wrote on Dec 4th, 2022 at 9:03pm:
There is no doubt the vaccinated like AusJeff the dopey bastard, Carl the Dunce and Buzz the arse fairy are more dangerous to us than we are to them. Billions of lives will be ended by this vax and I am glad its going to happen...

LOL... I actually got the best laugh of my otherwise boring
day after I read this.

My only complaint?   Please spell my name correctly if you're
gonna insult me.    It's GEOFF.   Thank you.    

                 Grin   



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Bobby.
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #5 - Dec 4th, 2022 at 10:17pm
 
Please learn how to resize pictures:

...
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Carl D
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #6 - Dec 4th, 2022 at 10:24pm
 
AusGeoff wrote on Dec 4th, 2022 at 10:15pm:
reggie1963 wrote on Dec 4th, 2022 at 9:03pm:
There is no doubt the vaccinated like AusJeff the dopey bastard, Carl the Dunce and Buzz the arse fairy are more dangerous to us than we are to them. Billions of lives will be ended by this vax and I am glad its going to happen...

LOL... I actually got the best laugh of my otherwise boring
day after I read this.

My only complaint?   Please spell my name correctly if you're
gonna insult me.    It's GEOFF.   Thank you.    

                 Grin   



Geoff, meet Reggie.

Sir Nail's 'backup', alleged cyber security expert and assistant forum chew toy.

LOL.  Grin Grin
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** Repeat Covid infections exercise our immune system in the same way that repeat concussions exercise our brain **
 
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reggie1963
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #7 - Dec 4th, 2022 at 10:32pm
 
Your authors conflict of interests are below. Look who they work for and who pays them. The same companies that make the drugs and the vaccines. Do you understand what the term "All outside of submitted work means"? Supplying a document that the authors receive payment from drug companies as irrefutable evidence that authors of another paper erred in their conclusions? Did you read and understand the their objections to what the authors said or did you just google and post a link?

You really are a dumb bastard mate. Every person that J. Barriere works with has a conflict of interest with other authors that receive payment from drug companies.

Like the rest of the brain dead idiots on here that took the vax I honestly hope you took it. I look forward to the day there are no more posts from you.


J. Barrière reports fees from BMS and Mylan Medical, all outside the submitted work. C. Audigier-Valette reports personal fees from AstraZeneca, Boehringer–Ingelheim, BMS, Lilly, Novartis, MSD, Pfizer, Roche AbbVie; grants from AstraZeneca, Boehringer–Ingelheim, BMS, Novartis, Roche MSD GSK; reimbursement for international meetings assistance from AstraZeneca, Boehringer–Ingelheim, BMS, Lilly, Novartis, Pfizer, Roche; all outside the submitted work. M. Carles, D. Re, A. Zoubir and B. Seitz-Polski have nothing to disclose. V. Gounant reports personal fees from MSD, Chugai, Novartis and Boehringer; personal fees and non-financial support from Astra Zeneca, BMS, Takeda and Pfizer; grants, personal fees, and non-financial support from Roche, all outside the submitted work; D. Descamps received honoraria and travel grants from ViiV Healthcare, Gilead Sciences, MSD and Janssen-Cilag, all outside the submitted work. G. Zalcman received research grants from Roche-France, BMS, and Takeda perceived fees from BMS, Astra-Zeneca, Pfizer and Borhinger-Ingelheim; reimbursement for international meetings assistance from AbbVie, MSD, Astra-Zeneca, BMS and Roche-France, all outside the submitted work.
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FROM CARL DUNCE THE LYING SACK OF HORSE SH*T

"The only gigantic lie we've been fed (and continue to be fed) by our governments is that Covid is mild and no more dangerous than the flu"
 
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reggie1963
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #8 - Dec 4th, 2022 at 10:35pm
 
Carl D wrote on Dec 4th, 2022 at 10:24pm:
AusGeoff wrote on Dec 4th, 2022 at 10:15pm:
reggie1963 wrote on Dec 4th, 2022 at 9:03pm:
There is no doubt the vaccinated like AusJeff the dopey bastard, Carl the Dunce and Buzz the arse fairy are more dangerous to us than we are to them. Billions of lives will be ended by this vax and I am glad its going to happen...

LOL... I actually got the best laugh of my otherwise boring
day after I read this.

My only complaint?   Please spell my name correctly if you're
gonna insult me.    It's GEOFF.   Thank you.    

                 Grin   



Geoff, meet Reggie.

Sir Nail's 'backup', alleged cyber security expert and assistant forum chew toy.

LOL.  Grin Grin



Still no link Carl? LIAR
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FROM CARL DUNCE THE LYING SACK OF HORSE SH*T

"The only gigantic lie we've been fed (and continue to be fed) by our governments is that Covid is mild and no more dangerous than the flu"
 
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Baronvonrort
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #9 - Dec 4th, 2022 at 10:41pm
 
Geert Vanden Bossche warned us  induced (vaccines) immunity will interfere with innate (natural) immunity.

Looks like Geert was right with the dangers of inducing your immune system to respond in a certain way which will then overpower your innate immunity leaving you defenceless against new variants.

Thread here showing 53% of covid deaths in this report from NSW health had 4 or more vax shots.
https://www.ozpolitic.com/forum/YaBB.pl?num=1668373929

Another win for those called conspiracy theorists. Wink
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Leftists and the Ayatollahs have a lot in common when it comes to criticism of Islam, they don't tolerate it.
 
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AusGeoff
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #10 - Dec 4th, 2022 at 11:18pm
 
reggie1963 wrote on Dec 4th, 2022 at 10:32pm:
Your authors conflict of interests are below...

The only author of the final paper in your list was Jérôme Barrière.  The other
scientists had no connection with the report  (where did you source the list?) 
Barrière reported fees all outside the submitted work.

This is a graphical representation of the errors made in https://www.sciencedirect.com/science/article/pii/S027869152200206X.

...


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AusGeoff
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #11 - Dec 4th, 2022 at 11:46pm
 
Baronvonrort wrote on Dec 4th, 2022 at 10:41pm:
Geert Vanden Bossche warned us  induced (vaccines) immunity will interfere with innate (natural) immunity.

Looks like Geert was right with the dangers of inducing your immune system to respond in a certain way which will then overpower your innate immunity leaving you defenceless against new variants.

Seriously?   Dr. Geert Vanden Bossche?  Check THIS site out to learn all about this anti-vaxxer nutjob.

Baronvonrort wrote on Dec 4th, 2022 at 10:41pm:
Thread here showing 53% of covid deaths in this report from NSW health had 4 or more vax shots.
https://www.ozpolitic.com/forum/YaBB.pl?num=1668373929

This simply proves you have no idea of how statistics work.  Tsk, tsk.

You've fallen for the phenomenon known as the "base rate fallacy".
In order to avoid the pitfalls of absolute numbers, one has to instead
look at incidence rates—usually expressed as the number of deaths
per 100,000 people. Standardising the denominator across all groups
offers a very different picture.

...
Credit: Amanda Montañez; Source: Centers for Disease Control and Prevention.

This shows that the unvaccinated are dying from COVID at nearly eight times the rate of the vaccinated.

Once again, the conspiracy theorists and anti-vaxxers fall flat on their faces.     Wink




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aquascoot
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #12 - Dec 5th, 2022 at 5:08am
 
a lot of this is impossible to assess.

one thing is for sure.

pharma companies are devoted to making profits, in that way they are as concerned about your health as tobaco companies or coal mining companies.

so there is NO WAY you can trust "their" science

the regulators at the fda and the tga are totally brought off.

16 of the last 20 directors and deputy directors of the FDA went on to work for big pharma companies when they left the FDA.

imagine if 16 out of 20 regulators of defence purchases went on to work for military manufactureres.

oh wait, they probably do.

this cant be sorted out until we get independant scientists to sort it out.

and when the universities and hospitals are also all brought off and profit driven, that wont be happening.

we still havent had an investigation into patient zero. the first step in investigating this.


all we can say for sure is that if you are unhealthy, you better work on your health because more variants are coming FOR SURE and the vaccines in no way stop the spread.

i expect big pharma to move over to the treatment model.

with paxlovid earning them about 100 bucks a tablet and covid remaining rampant, that would appear to be the new river of gold  Roll Eyes Roll Eyes Roll Eyes
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Baronvonrort
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #13 - Dec 5th, 2022 at 8:11am
 
aquascoot wrote on Dec 5th, 2022 at 5:08am:
a lot of this is impossible to assess.

one thing is for sure.

pharma companies are devoted to making profits, in that way they are as concerned about your health as tobaco companies or coal mining companies.

so there is NO WAY you can trust "their" science


the regulators at the fda and the tga are totally brought off.

16 of the last 20 directors and deputy directors of the FDA went on to work for big pharma companies when they left the FDA.

imagine if 16 out of 20 regulators of defence purchases went on to work for military manufactureres.

oh wait, they probably do.

this cant be sorted out until we get independant scientists to sort it out.

and when the universities and hospitals are also all brought off and profit driven, that wont be happening.

we still havent had an investigation into patient zero. the first step in investigating this.


all we can say for sure is that if you are unhealthy, you better work on your health because more variants are coming FOR SURE and the vaccines in no way stop the spread.

i expect big pharma to move over to the treatment model.

with paxlovid earning them about 100 bucks a tablet and covid remaining rampant, that would appear to be the new river of gold  Roll Eyes Roll Eyes Roll Eyes


Governments gave big pharma indemnity from lawsuits for adverse effects which gave them a green light to push these vaccines without consequences to boost their profits.

This was a huge mistake.
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Leftists and the Ayatollahs have a lot in common when it comes to criticism of Islam, they don't tolerate it.
 
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Baronvonrort
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Re: Innate immune suppression by SARS-CoV-2 mRNA vax
Reply #14 - Dec 5th, 2022 at 8:22am
 
AusGeoff wrote on Dec 4th, 2022 at 11:46pm:
Baronvonrort wrote on Dec 4th, 2022 at 10:41pm:
Geert Vanden Bossche warned us  induced (vaccines) immunity will interfere with innate (natural) immunity.

Looks like Geert was right with the dangers of inducing your immune system to respond in a certain way which will then overpower your innate immunity leaving you defenceless against new variants.

Seriously?   Dr. Geert Vanden Bossche?  Check THIS site out to learn all about this anti-vaxxer nutjob.

Baronvonrort wrote on Dec 4th, 2022 at 10:41pm:
Thread here showing 53% of covid deaths in this report from NSW health had 4 or more vax shots.
https://www.ozpolitic.com/forum/YaBB.pl?num=1668373929

This simply proves you have no idea of how statistics work.  Tsk, tsk.

You've fallen for the phenomenon known as the "base rate fallacy".
In order to avoid the pitfalls of absolute numbers, one has to instead
look at incidence rates—usually expressed as the number of deaths
per 100,000 people. Standardising the denominator across all groups
offers a very different picture.

https://i.postimg.cc/MKGRCRW0/covid-Deaths-graphic-d2-1.png
Credit: Amanda Montañez; Source: Centers for Disease Control and Prevention.

This shows that the unvaccinated are dying from COVID at nearly eight times the rate of the vaccinated.

Once again, the conspiracy theorists and anti-vaxxers fall flat on their faces.     Wink






Unlike you i don't cherry pick stats or call those who question anything conspiracy theorists.

Since you ignore this question in another thread how effective are these vaccines when our ABS statistics show a 99.9% survival rate for those under 60 who caught Covid?

Quote:
Case fatality rate


The graph below shows that while the CFR for those aged under 60 years is 0.1%, the CFR for males aged over 90 years is over 50%.


https://www.abs.gov.au/articles/covid-19-mortality-australia-deaths-registered-3...


Was our vaccination rate below 20% when those under 60 had a 99.9% survival rate with the far more deadly Delta variant?

Does our CFR of over 50% for those over 90 show the epidemiologists from Harvard, Stanford and Oxford who wrote the Great Barrington Declaration were right with saying we should focus protection on the elderly? Did Fauci call these people fringe epidemiologists?
History shows the GBD nailed it and Fauci was a huge failure.

Have a look on CDC data thread i posted what are the major risks for Covid?
Did it say Age, Obesity and Diabetes were the 3 major risks?
Did it also show those who died had 3 or more comorbidities?

With our 99.9% survival rate for those under 60 i wonder how many of the 0.1% who died were Obese or had diabetes.




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Leftists and the Ayatollahs have a lot in common when it comes to criticism of Islam, they don't tolerate it.
 
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