There is no reason why humans wouldn't be able to work out what this "universal rule" is.
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Well, face to huge universe, the capability of human are not small, but could be tiny.
some times we think we are the host of Earth, but dinosaurs would think like us.
Where is dinosaurs nowadays?
Some one say, they are chicken now.
Chicken is not the host of Earth so neither human.
We are not the host of Universe and Earth.
When we are here we can sense there is a universal rule.
We can approach and obey it.